LipidSig 2.0: Integrating Lipid Characteristic Insights into Advanced Lipidomics Data Analysis

What is LipidSig?

LipidSig is the first web-based platform which integrates a comprehensive analysis for streamlined data mining of lipidomic datasets.

The user-friendly interface provides two helper functions, Data Check, ID Conversion, and six analytical functions: Profiling, Differential Expression, Enrichment, Machine Learning, Correlation and Network.

The two helper functions offer format verification for user-uploaded data, map to 9 resource IDs, and automatically assign 29 lipid characteristics based on the uploaded features.

The six analytical functions are designed for the assessment of lipid effects on biological mechanisms and provide unique aspects to analyze the lipidome profiling data based on different characteristics, including lipid class, chain length, unsaturation, hydroxyl group, and fatty acid composition. Users can perform intensive lipid analysis and create interactive plots with downloadable images and corresponding tables.

LipidSig is free and open to all users and provides downloadable example datasets in each analysis section.

News & Updates

  • 2023 12.01 Launch of LipidSig 2.0
  • 2021.10.08 User experience improvement of LipidSig.
  • 2021.07.02 Publish of LipidSig at NAR !
  • 2021.03.01 Launch of Machine Learning feature.
  • 2021.01.01 Launch of LipidSig!

Chia-Hsin Liu, Pei-Chun Shen, Wen-Jen Lin, Hsiu-Cheng Liu, Meng-Hsin Tsai, Tzu-Ya Huang, I-Chieh Chen, Yo-Liang Lai, Yu-De Wang, Mien-Chie Hung, Wei-Chung Cheng. LipidSig 2.0: integrating lipid characteristic insights into advanced lipidomics data analysis. Nucleic Acids Res.2024 May 6. doi: 10.1093/nar/gkae335. PMID: 38709887.

Schematic representation of LipidSig